منابع مشابه
Molecular genetics of neurological tumours.
Recent developments in our understanding of neoplastic transformation and tumorigenesis have largely paralleled technical advances in molecular and cellular biology. A great deal of work has been focused in the past two decades upon tumour types which claim vast numbers yearly, for example, cancers of the breast, lung, colon, blood, and bone. However, many basic genetic aberrations first detect...
متن کاملRenal Tumours in Adults with Correlation between Fuhrman Grading and Proliferative Marker
Background: Definite data regarding the incidence and distribution of renal tumours in eastern India is not known. For better management, as it is essential to identify patients with poor prognosis, prognostic factors like stage, nuclear grade and their relationship to molecular markers are also unclear in this region. The purpose of our study was to assess the spectrum of adu...
متن کاملMolecular medicine imaging of neuroendocrine tumours
Neuroendocrine tumours (NETs) are a diverse, highly heterogeneous group of neoplasms derived from endocrine cells found in the neural crest. NETs typically display endocrine metabolism and slow growth, while displaying a wide range of presentations and clinical symptoms. Demonstrating typically small lesions, with varying anatomical localisation, diagnosis is typically in the advanced stages of...
متن کاملNext-generation molecular genetics of brain tumours.
PURPOSE OF REVIEW Systematic use of next-generation sequencing technologies has transformed the field of cancer genomics, leading to the identification of genetic alterations in an unanticipated number of genes and regulatory elements. Here, we review recent advances in brain tumour genomics and highlight how these findings improve classification and diagnosis of brain tumours. RECENT FINDING...
متن کاملThe molecular genomics of metastatic brain tumours.
INTRODUCTION Metastatic brain tumours remain an intractable clinical problem despite notable advances in the treatment of the primary cancers. It is estimated that 30-40% of breast and lung cancer patients will develop brain metastases. Typically, brain lesions are not diagnosed until patients exhibit neurological symptoms because there are currently no tests that can predict which patients wil...
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ژورنال
عنوان ژورنال: Journal of Cancer Therapy
سال: 2016
ISSN: 2151-1934,2151-1942
DOI: 10.4236/jct.2016.710070